September 25, 2023 at 9:45 am #54170Joseph newBrownParticipant
Vigora 50 is a medication that contains the active ingredient sildenafil citrate, which is commonly used to treat erectile dysfunction (ED). To understand how Vigora 50 works, it’s essential to know the underlying mechanism behind its potency:
Phosphodiesterase Type 5 (PDE5) Inhibition: Vigora 50, like other ED medications such as Viagra, is a PDE5 inhibitor. PDE5 is an enzyme found in the smooth muscle cells of blood vessels, including those in the penis. When sexually stimulated, the body releases nitric oxide, which triggers the production of a molecule called cyclic guanosine monophosphate (cGMP).
cGMP Role: cGMP is responsible for relaxing the smooth muscle cells in the penile arteries, leading to increased blood flow into the penis. This increased blood flow is essential for achieving and maintaining an erection. However, PDE5 naturally breaks down cGMP, limiting its effects.
Sildenafil’s Action: Sildenafil citrate, the active ingredient in Vigora 50 mg tablet, works by inhibiting PDE5. By doing so, it prevents the premature breakdown of cGMP. This allows cGMP to accumulate in the penile tissues, leading to prolonged and improved blood flow into the penis, which helps a man achieve and sustain an erection when sexually aroused.
Need for Sexual Stimulation: It’s important to note that Vigora 50 does not cause spontaneous erections. Sexual arousal and stimulation are still required for it to be effective. In the presence of sexual stimulation, the medication enhances the natural process of erection by optimizing blood flow.
Duration of Effect: The effects of Vigora 50 typically last for several hours, during which time a man may find it easier to get and maintain an erection. The duration of action can vary from person to person but generally ranges from 4 to 6 hours.
Dosage and Timing: The appropriate dosage of Vigora 50 should be determined by a healthcare provider based on individual needs and health considerations. It is usually taken orally about 30 minutes to an hour before anticipated sexual activity.
It’s important to use Vigora 50 (or any medication containing sildenafil) as directed by a healthcare professional and to discuss any potential side effects, drug interactions, or underlying health conditions with them. Additionally, avoid using Vigora 50 in combination with nitrates or other medications that can interact with sildenafil, as this can lead to a dangerous drop in blood pressure. Always consult with a healthcare provider for personalized guidance on using ED medications safely and effectively.
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