The BIOEAST HUB Czech Republic organised FreshWater Clustering event organized in a hybrid from in Brussels on the 19th of March to show good practice related to fresh water, discuss BIOEAST macro-regional priorities and intensify the involvement in the international collaboration. The event aimed to illustrate the importance of the “freshwater” topic and highlight the need for further research, innovation, and investment to tackle the scarcity of natural resources and related issues of sustainability, food and energy security, and solution for societal impasse.