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Avanafil, marketed under the brand name Stendra or Spedra, is a medication used to treat erectile dysfunction (ED) in men. Like any medication, it can interact with other drugs, potentially leading to contraindications or adverse effects. Here are some common medications that may have contraindications or interactions with Avanafil:
Nitrates: Taking Avana with nitrates, commonly prescribed for chest pain or heart conditions, can cause a severe drop in blood pressure, leading to dizziness, fainting, or even a heart attack. It’s essential to avoid combining avanafil with nitrates.
Alpha-blockers: Alpha-blockers, used to treat high blood pressure and prostate conditions, can also cause a drop in blood pressure when taken with avanafil. Combining these medications can increase the risk of low blood pressure and its associated symptoms.
Antifungal Medications: Some antifungal medications, such as ketoconazole and itraconazole, can increase the levels of avanafil in the body, potentially leading to an increased risk of side effects. Your healthcare provider may need to adjust the dosage of avanafil if you are taking these medications.
HIV Protease Inhibitors: HIV protease inhibitors, used to treat HIV/AIDS, can also increase avanafil levels in the body, increasing the risk of side effects. Adjustments to the avanafil dosage may be necessary if you are taking these medications.
Other PDE5 Inhibitors: Using avanafil with other phosphodiesterase type 5 (PDE5) inhibitors, such as sildenafil (Viagra), tadalafil (Cialis), or vardenafil (Levitra), can potentiate the effects of avanafil and increase the risk of adverse effects. Combining these medications is generally not recommended.
It’s crucial to inform your healthcare provider about all medications you are currently taking, including prescription drugs, over-the-counter medications, and herbal supplements, before starting treatment with avanafil. Your healthcare provider can assess the potential for interactions and contraindications and adjust your treatment plan accordingly to ensure your safety and efficacy of the medication.
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Yes, Avana (avanafil) may have contraindications with other medications, particularly those containing nitrates or nitric oxide donors, such as nitroglycerin. Concurrent use of Avana with nitrates can cause a severe drop in blood pressure, leading to dizziness, fainting, or even a heart attack. Additionally, Avana should not be used with certain medications used to treat HIV/AIDS, such as ritonavir and indinavir, as well as certain antifungal medications like ketoconazole and itraconazole, which can increase avanafil levels in the blood, leading to an increased risk of adverse effects. Individuals should inform their healthcare provider about all medications they are currently taking before starting Avana to ensure it is safe and appropriate for them. It’s crucial to follow the guidance of a healthcare professional and read the medication label carefully for any potential drug interactions or contraindications.
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